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G Y, Wang S, Spiro D, Ghedin E, Carlow CK: Mining predicted essential genes of Brugia malayi for nematode drug targets. PLoS One 2007, 2(11):e1189. 131. Foster JM, Zhang Y, Kumar S, Carlow CK: Mining nematode genome data for novel drug targets. Trends Parasitol 2005, 21(3):101-104.doi:10.1186/1471-2164-13-S7-S10 Cite this article as: Menon et al.: An analysis of the transcriptome of Teladorsagia c
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Ilage (Jofuku et al., 1994; Western et al., 2001; Dean et al., 2011). Since mucilage can only be extracted from hydrated Col-0 seeds, proteins that are significantly overrepresented in Col-0 nonadherent mucilage compared with mum2-10 and/or ap2-7 seed surface extracts would be predicted to be derived from the extruded mucilage. Several mucilage proteins identified were indeed found at much higher
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Nsible for discrete receptor-binding properties, consists of multiple duffy binding-like (DBL) domains and cysteinerich interdomain regions (CIDRs) [74?6]. Table 1 summarizes the lines of evidence that support the role of VAR2CSA.Table 1: Evidence providing support for the integral role of VAR2CSA in placental malaria. Evidence Placental parasites selectively transcribe the var2csa gene The var2cs
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In a schematic of a eukaryotic cell.are indicated by color and single residue pins. Depending on the protein, the overview features may include predictions of secondary structure and solvent accessibility, transmembrane helices, disulfide bonds and disordered regions. Details are available by zooming-in on local regions. Other views present additional annotations and predictions, e.g. functional l
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In a schematic of a eukaryotic cell.are indicated by color and single residue pins. Depending on the protein, the overview features may include predictions of secondary structure and solvent accessibility, transmembrane helices, disulfide bonds and disordered regions. Details are available by zooming-in on local regions. Other views present additional annotations and predictions, e.g. functional l
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Robe sets for CB1R, CB2R, FAAH, MAGL, vascular endothelial growth factor A (VEGF-A), apoptotic protease activating factor 1 (APAF), caspase 3, and caspase 9 were purchased from Applied Biosystems (Grand Island, NY). All reactions were performed in triplicate and 18S ribosomal RNA, amplified using the Taqman Ribosomal RNA control kit, served as an internal control. The results were quantified as Ct
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Robe sets for CB1R, CB2R, FAAH, MAGL, vascular endothelial growth factor A (VEGF-A), apoptotic protease activating factor 1 (APAF), caspase 3, and caspase 9 were purchased from Applied Biosystems (Grand Island, NY). All reactions were performed in triplicate and 18S ribosomal RNA, amplified using the Taqman Ribosomal RNA control kit, served as an internal control. The results were quantified as Ct
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Ithout hyperfibrinolysis (41.7 ). Stepwise logistic regression analyses confirmed that DIC, SOFA scores, and lactate levels are independent predictors of patient death. Hyperfibrinolysis also predicted patient death. Tissue hypoperfusion (as indicated by lactate level) is a main determinant of hyperfibrinolysis. Receiver operating characteristic curves showed a significant discriminative performa
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Ss application charges were borne byMenon et al. BMC Genomics 2012, 13(Suppl 7):S10 http://www.biomedcentral.com/1471-2164/13/S7/SPage 15 of12. Smith SK, Nisbet AJ, Meikle LI, Inglis NF, Sales J, Beynon RJ, Matthews JB: Proteomic analysis of excretory/secretory products released by Teladorsagia circumcincta larvae early post-infection. Parasite Immunol 2009, 31(1):10-19. 13. Nisbet AJ, Zarlenga DS
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Ss application charges were borne byMenon et al. BMC Genomics 2012, 13(Suppl 7):S10 http://www.biomedcentral.com/1471-2164/13/S7/SPage 15 of12. Smith SK, Nisbet AJ, Meikle LI, Inglis NF, Sales J, Beynon RJ, Matthews JB: Proteomic analysis of excretory/secretory products released by Teladorsagia circumcincta larvae early post-infection. Parasite Immunol 2009, 31(1):10-19. 13. Nisbet AJ, Zarlenga DS
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Se proteins are tightly clustered on chromosome 1, suggesting that the gene family may have expanded through tandem duplication events. Due to the abundance of the UPF0540 proteins in the seed coat, these genes were named TESTA ABUNDANT1 (TBA1; At1g62000/Q39168), TBA2 (At1g62060/O04573), and TBA3 (At1g62080/O04575). Interestingly, a peptide from a fourth member of the UPF0540 family, At1g62220/O04
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